Lei Sun's Publications

  1. Wright et al. (2011). Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2. Nature Genetics 43:539-548.

  2. Faye L, Sun L, Dimitromanolakis A, Bull SB (2011). A flexible genome-wide bootstrap method that accounts for ranking- and threshold-selection bias in GWAS interpretation and replication study design. Statistics in Medicine 30:1898-1912.

  3. Sun L (2011). On the efficiency of genome-wide scans: a multiple hypothesis testing perspective. U.P.B. Sci. Bull., Series A., 73(1):19-26.

  4. Sun L, Dimitromanolakis A, Faye L, Paterson AD, Waggott D, the DCCT/EDIC Research Group, Bull SB (2011). BRsquared: a practical solution to the winner's curse in genome-wide scans. Human Genetics 129:545-552

  5. Dorfman R et al. (2011). Modulatory effect of the SLC9A3 gene on susceptibility to infections and pulmonary function in children with cystic fibrosis. Pediatric Pulmonology 46(4):385-392.

  6. Li W et al. (2011). Understanding the population structure of North American patients with Cystic Fibrosis. Clinical Genetics 79:136-146.

  7. Xu L, Craiu RV, Sun L (2011). Bayesian methods to overcome the winner's curse in genetic studies. Annals of Applied Statistics 5(1):201-231.

  8. Mirea L, Sun L, Stafford JE, Bull SB (2010). Using evidence for population stratification bias in combined individual- and family-level genetic association analyses of quantitative traits. Genetic Epidemiology 34:502-511.

  9. Paterson AD et al. (2010). A genome-wide association study identifies a novel major locus for glycemic control in type 1 diabetes, as measured by both HbA1c and glucose. Diabetes 59:539-549.

  10. Yoo YJ, Bull SB, Paterson AD, Waggott D, The DCCT/EDIC Research Group, Sun L (2010). Were genome-wide linkage studies a waste of time? Exploiting candidate regions within genome-wide association studies. Genetic Epidemiology 34:107-118.

  11. Paterson AD et al. (2009). Genome-wide association identifies the ABO blood group as a major locus associated with serum levels of soluble E-Selectin. Arteriosclerosis, Thrombosis, and Vascular Biology 29:1958-1967

  12. Dorfman R et al. (2009). Modifier gene study of Meconium Ileus in Cystic Fibrosis: statistical considerations and gene mapping results. Human Genetics 126:763-778.

  13. Yoo YJ, Pinnaduwage D, Waggott D, Bull SB, Sun L (2009). Association analyses of genome-wide SNP data of NARAC and FHS utilizing genome-wide linkage results. BMC Proceedings 3:S103.

  14. Asimit J, Yoo YJ, Waggott D, Sun L, Bull SB (2009). Region-based analysis in genome-wide association study of Framingham Heart Study blood lipid phenotypes. BMC Proceedings 3:S127.

  15. Craiu RV, Sun L (2008). Choosing the lesser evil: trade-off between false discovery rate and non-discovery rate. Statistica Sinica 18:861-879.

  16. Lee SSF, Sun L, Kustra R, Bull SB (2008). EM-random forest and new measures of variable importance for multi-Locus quantitative trait linkage analysis. Bioinformatics 24:1603-1610.

  17. Dorfman R et al. (2008). Complex two-gene modulation of lung disease severity in children with cystic fibrosis. Journal of Clinical Investigation 118:1040-1049.

  18. Al-Kateb H et al. (2008). Multiple SOD1 / SFRS15 variants are associated with the development and progression of diabetic nephropathy: The DCCT/EDIC Genetics study. Diabetes 57:218-228.

  19. Al-Kateb H et al. (2007). Multiple variants in Vascular Endothelial Growth Factor (VEGF) are risk factors for time to severe retinopathy in type 1 diabetes: The DCCT/EDIC genetics study. Diabetes 56:2161-2168.

  20. Huang B, Rangreg J, Paterson AD, Sun L (2007). The multiplicity problem in linkage analysis of gene expression data - the power of differentiating cis- and trans-acting regulators. BMC Proceedings 1:S142. Supplementary material: Figures 1 and 2.

  21. Greenwood C, Rangreg J, Sun L (2007). Optimal selection of markers for validation from genome-wide association studies. Genetic Epidemiology 31:396-407.

  22. Wu LY, Sun L, Bull SB (2006). Locus-specific heritability estimation via the bootstrap in linkage scans for quantitative trait loci. Human Heredity 62:84-96.

  23. Sun L, Craiu RV, Paterson AD and Bull SB (2006). Stratified false discovery control for large-scale hypothesis testing with application to genome-wide association studies. Genetic Epidemiology 30:519-530.

  24. Wu LY, Lee SSF, Shi HS, Sun L, Bull SB (2005). Resampling methods to reduce the selection bias in genetic effect estimation in genome-wide scans. Genetic Analysis Workshop 14: Microsatellite and single-nucleotide polymorphism. BMC Genetics 6:S24.

  25. Biernacka J, Sun L, Bull SB (2005). Tests for the presence of two linked disease susceptibility genes. Genetic Epidemiology 29:389-401.

  26. Sun L, Bull SB (2005). Reduction of selection bias in genomewide genetic studies by resampling. Genetic Epidemiology 28:352-367.

  27. Biernacka J, Sun L, Bull SB (2005). Simultaneous localization of two linked disease susceptibility genes. Genetic Epidemiology 28:33-47.

  28. Paterson AD, Sun L, Liu XQ (2003). Transmission ratio distortion in families from the Framingham Heart Study. Genetic Analysis Workshop 13: Analysis of longitudinal family data for complex diseases and related risk factors. BMC Genetics 4:S48.

  29. Strug L, Sun L, Corey M (2003). The Genetics of Cross-Sectional and Longitudinal BMI. Genetic Analysis Workshop 13: Analysis of longitudinal family data for complex diseases and related risk factors. BMC Genetics 4:S14.

  30. Sun L, Wilder K, McPeek MS (2002). Enhanced pedigree error detection. Human Heredity 54:99-110.

  31. Sun L, Cox NJ, McPeek MS (2002). A statistical method for identification of polymorphisms that explain a linkage result. American Journal of Human Genetics 70:399-411.

  32. Sun L, Abney M, McPeek MS (2001). Detection of misspecified relationships in inbred and outbred pedigrees. Genetic Analysis Workshop 12: Analysis of complex genetic traits: Applications to asthma and simulated data. Genetic Epidemiology 21:S36-41.

  33. McPeek MS, Sun L (2000). Statistical tests for detection of misspecified relationships by use of genome-screen data. American Journal of Human Genetics 66:1076-1094.