Results: monkey1.sas

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The MEANS Procedure

The Means Procedure

Summary statistics

treatmnt N Obs Variable Label Mean
CONTROL 7
week2
week4
week8
week12
week16
Trained 2 weeks before injection
Trained 4 weeks before injection
Trained 8 weeks before injection
Trained 12 weeks before injection
Trained 16 weeks before injection
78.5714286
82.1428571
70.7142857
62.1428571
70.0000000
TREATED 11
week2
week4
week8
week12
week16
Trained 2 weeks before injection
Trained 4 weeks before injection
Trained 8 weeks before injection
Trained 12 weeks before injection
Trained 16 weeks before injection
62.2727273
64.0909091
65.4545455
72.2727273
67.2727273

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

The GLM Procedure

Data

Class Levels

Class Level Information
Class Levels Values
treatmnt 2 CONTROL TREATED

Number of Observations

Number of Observations Read 18
Number of Observations Used 18

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

 

Dependent Variable: week2 Trained 2 weeks before injection

Analysis of Variance

week2

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 1136.381674 1136.381674 10.37 0.0054
Error 16 1753.896104 109.618506    
Corrected Total 17 2890.277778      

Fit Statistics

R-Square Coeff Var Root MSE week2 Mean
0.393174 15.25975 10.46989 68.61111

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 1136.381674 1136.381674 10.37 0.0054

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 1136.381674 1136.381674 10.37 0.0054

Box Plot

Fit Plot for Trained 2 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

 

Dependent Variable: week4 Trained 4 weeks before injection

week4

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 1394.011544 1394.011544 17.37 0.0007
Error 16 1283.766234 80.235390    
Corrected Total 17 2677.777778      

Fit Statistics

R-Square Coeff Var Root MSE week4 Mean
0.520585 12.59637 8.957421 71.11111

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 1394.011544 1394.011544 17.37 0.0007

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 1394.011544 1394.011544 17.37 0.0007

Box Plot

Fit Plot for Trained 4 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

 

Dependent Variable: week8 Trained 8 weeks before injection

week8

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 118.344156 118.344156 1.15 0.2991
Error 16 1644.155844 102.759740    
Corrected Total 17 1762.500000      

Fit Statistics

R-Square Coeff Var Root MSE week8 Mean
0.067146 15.01785 10.13705 67.50000

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 118.3441558 118.3441558 1.15 0.2991

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 118.3441558 118.3441558 1.15 0.2991

Box Plot

Fit Plot for Trained 8 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

 

Dependent Variable: week12 Trained 12 weeks before injection

week12

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 438.961039 438.961039 4.50 0.0499
Error 16 1561.038961 97.564935    
Corrected Total 17 2000.000000      

Fit Statistics

R-Square Coeff Var Root MSE week12 Mean
0.219481 14.45487 9.877496 68.33333

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 438.9610390 438.9610390 4.50 0.0499

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 438.9610390 438.9610390 4.50 0.0499

Box Plot

Fit Plot for Trained 12 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

 

Dependent Variable: week16 Trained 16 weeks before injection

week16

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 31.818182 31.818182 0.31 0.5826
Error 16 1618.181818 101.136364    
Corrected Total 17 1650.000000      

Fit Statistics

R-Square Coeff Var Root MSE week16 Mean
0.019284 14.71706 10.05666 68.33333

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 31.81818182 31.81818182 0.31 0.5826

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 31.81818182 31.81818182 0.31 0.5826

Box Plot

Fit Plot for Trained 16 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

Repeated Measures Analysis of Variance

Repeated Measures Analysis

Level Information

Repeated Measures Level Information
Dependent Variable week2 week4 week8 week12 week16
Level of time 1 2 3 4 5

MANOVA

Model

time

Multivariate Tests

MANOVA Test Criteria and Exact F Statistics for the Hypothesis of no time Effect
H = Type III SSCP Matrix for time
E = Error SSCP Matrix

S=1 M=1 N=5.5
Statistic Value F Value Num DF Den DF Pr > F
Wilks' Lambda 0.84009249 0.62 4 13 0.6571
Pillai's Trace 0.15990751 0.62 4 13 0.6571
Hotelling-Lawley Trace 0.19034512 0.62 4 13 0.6571
Roy's Greatest Root 0.19034512 0.62 4 13 0.6571

time*treatmnt

Multivariate Tests

MANOVA Test Criteria and Exact F Statistics for the Hypothesis of no time*treatmnt Effect
H = Type III SSCP Matrix for time*treatmnt
E = Error SSCP Matrix

S=1 M=1 N=5.5
Statistic Value F Value Num DF Den DF Pr > F
Wilks' Lambda 0.44106117 4.12 4 13 0.0227
Pillai's Trace 0.55893883 4.12 4 13 0.0227
Hotelling-Lawley Trace 1.26725921 4.12 4 13 0.0227
Roy's Greatest Root 1.26725921 4.12 4 13 0.0227

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

Repeated Measures Analysis of Variance

Tests of Hypotheses for Between Subjects Effects

Between Effects Tests

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 887.503608 887.503608 8.08 0.0118
Error 16 1758.051948 109.878247    

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

Repeated Measures Analysis of Variance

Univariate Tests of Hypotheses for Within Subject Effects

Within

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F Adj Pr > F
G - G H-F-L
time 4 375.346320 93.836580 0.98 0.4227 0.4164 0.4227
time*treatmnt 4 2232.012987 558.003247 5.85 0.0004 0.0009 0.0004
Error(time) 64 6102.987013 95.359172        

Epsilons

Greenhouse-Geisser Epsilon 0.8786
Huynh-Feldt-Lecoutre Epsilon 1.1563

Summary

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

Repeated Measures Analysis of Variance

Analysis of Variance of Contrast Variables

 

time_N represents the nth successive difference in time

Contrast Variable: time_1

time_1

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
Mean 1 124.260462 124.260462 0.66 0.4275
treatmnt 1 13.149351 13.149351 0.07 0.7945
Error 16 2999.350649 187.459416    

Contrast Variable: time_2

time_2

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
Mean 1 433.351371 433.351371 2.08 0.1689
treatmnt 1 700.018038 700.018038 3.35 0.0858
Error 16 3340.259740 208.766234    

Contrast Variable: time_3

time_3

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
Mean 1 13.149351 13.149351 0.08 0.7797
treatmnt 1 1013.149351 1013.149351 6.24 0.0238
Error 16 2599.350649 162.459416    

Contrast Variable: time_4

time_4

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
Mean 1 34.920635 34.920635 0.33 0.5736
treatmnt 1 707.142857 707.142857 6.68 0.0199
Error 16 1692.857143 105.803571    

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

The GLM Procedure

Repeated Measures Analysis of Variance

 

Means of Within Subjects Effects

Means of Within Subjects Effects

Level of
time		 N Mean Std Dev
1 18 68.61111111 13.03903140
2 18 71.11111111 12.55055138
3 18 67.50000000 10.18216434
4 18 68.33333333 10.84652289
5 18 68.33333333 9.85184366

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

The GLM Procedure

Data

Class Levels

Class Level Information
Class Levels Values
treatmnt 2 CONTROL TREATED

Number of Observations

Number of Observations Read 18
Number of Observations Used 18

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

 

Dependent Variable: week2 Trained 2 weeks before injection

Analysis of Variance

week2

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 1136.381674 1136.381674 10.37 0.0054
Error 16 1753.896104 109.618506    
Corrected Total 17 2890.277778      

Fit Statistics

R-Square Coeff Var Root MSE week2 Mean
0.393174 15.25975 10.46989 68.61111

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 1136.381674 1136.381674 10.37 0.0054

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 1136.381674 1136.381674 10.37 0.0054

Box Plot

Fit Plot for Trained 2 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

 

Dependent Variable: week4 Trained 4 weeks before injection

week4

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 1394.011544 1394.011544 17.37 0.0007
Error 16 1283.766234 80.235390    
Corrected Total 17 2677.777778      

Fit Statistics

R-Square Coeff Var Root MSE week4 Mean
0.520585 12.59637 8.957421 71.11111

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 1394.011544 1394.011544 17.37 0.0007

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 1394.011544 1394.011544 17.37 0.0007

Box Plot

Fit Plot for Trained 4 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

 

Dependent Variable: week8 Trained 8 weeks before injection

week8

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 118.344156 118.344156 1.15 0.2991
Error 16 1644.155844 102.759740    
Corrected Total 17 1762.500000      

Fit Statistics

R-Square Coeff Var Root MSE week8 Mean
0.067146 15.01785 10.13705 67.50000

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 118.3441558 118.3441558 1.15 0.2991

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 118.3441558 118.3441558 1.15 0.2991

Box Plot

Fit Plot for Trained 8 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

 

Dependent Variable: week12 Trained 12 weeks before injection

week12

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 438.961039 438.961039 4.50 0.0499
Error 16 1561.038961 97.564935    
Corrected Total 17 2000.000000      

Fit Statistics

R-Square Coeff Var Root MSE week12 Mean
0.219481 14.45487 9.877496 68.33333

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 438.9610390 438.9610390 4.50 0.0499

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 438.9610390 438.9610390 4.50 0.0499

Box Plot

Fit Plot for Trained 12 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

 

Dependent Variable: week16 Trained 16 weeks before injection

week16

Overall ANOVA

Source DF Sum of Squares Mean Square F Value Pr > F
Model 1 31.818182 31.818182 0.31 0.5826
Error 16 1618.181818 101.136364    
Corrected Total 17 1650.000000      

Fit Statistics

R-Square Coeff Var Root MSE week16 Mean
0.019284 14.71706 10.05666 68.33333

Type I Model ANOVA

Source DF Type I SS Mean Square F Value Pr > F
treatmnt 1 31.81818182 31.81818182 0.31 0.5826

Type III Model ANOVA

Source DF Type III SS Mean Square F Value Pr > F
treatmnt 1 31.81818182 31.81818182 0.31 0.5826

Box Plot

Fit Plot for Trained 16 weeks before injection by treatmnt

Primate hippocampal function: Zola-Morgan and Squire (1990)

Multivariate approach to repeated measures (within-cases)

MANOVA, no repeated measures

The GLM Procedure

Multivariate Analysis of Variance

Multivariate Analysis of Variance

Model MANOVA

treatmnt

Characteristic Structure

Characteristic Roots and Vectors of: E Inverse * H, where
H = Type III SSCP Matrix for treatmnt
E = Error SSCP Matrix
Characteristic Root Percent Characteristic Vector V'EV=1
week2 week4 week8 week12 week16
2.33092613 100.00 0.01069187 0.01967655 0.01073552 -0.01222695 0.01040631
0.00000000 0.00 0.00224348 0.01227263 -0.00156297 0.02492720 0.00096044
0.00000000 0.00 -0.00401479 -0.00281033 0.02352231 0.00045709 -0.00107182
0.00000000 0.00 -0.01061455 -0.00326973 0.00566476 -0.01223797 0.02869687
0.00000000 0.00 -0.01901465 0.01716790 0.00000000 0.00000000 0.00000000

Multivariate Tests

MANOVA Test Criteria and Exact F Statistics for the Hypothesis of No Overall treatmnt Effect
H = Type III SSCP Matrix for treatmnt
E = Error SSCP Matrix

S=1 M=1.5 N=5
Statistic Value F Value Num DF Den DF Pr > F
Wilks' Lambda 0.30021681 5.59 5 12 0.0069
Pillai's Trace 0.69978319 5.59 5 12 0.0069
Hotelling-Lawley Trace 2.33092613 5.59 5 12 0.0069
Roy's Greatest Root 2.33092613 5.59 5 12 0.0069